Two sample MR report
FAM3B_Dendritic Cell (DC) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0879544 | 0.0768017 | 0.4569714 |
| Weighted median | 3 | -0.0181272 | 0.0091401 | 0.0473380 |
| Inverse variance weighted | 3 | -0.0202607 | 0.0069419 | 0.0035157 |
| Simple mode | 3 | -0.0169287 | 0.0108506 | 0.2590876 |
| Weighted mode | 3 | -0.0162248 | 0.0106592 | 0.2673980 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4333413 | 1 | 0.5103539 |
| Inverse variance weighted | 1.2166221 | 2 | 0.5442693 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.095286 | 0.107664 | 0.5387795 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.59e-05 | 0 | TRUE | 0.5224517 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
